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Is it harmful to take a coenzyme Q10 (CoQ10) supplement along with Zetia to help prevent muscle-related side effects? But if they become more severe or dont go away, talk with your doctor or pharmacist. POTS is defined by its particular symptoms and an excessive increase in heart rate upon standing. Zetia may also increase the amount of cholesterol thats stored in your gallbladder. Clinical studies for ezetimibe did not note any difference in weight in those that took the drug versus those that did not. In studies, weight changes didnt occur in people who took the drug. Your doctor may do liver function tests before you start treatment and regularly during your Zetia treatment. This helps prevent others, including children and pets, from taking the drug by accident. Ezetimibe may be used alone or with other drugs (such as "statins" or . Pots or postural tachycardia syndrome is, also known as postural orthostatic tachycardia syndrome, is a condition that affects the flow of blood in the heart and brain. The heart beats faster to pump it up to the brain, but with little success. Zetia reduces the buildup of fats, cholesterol, and other substances on the artery walls (this process is known as atherosclerosis) and if taken long term it may reduce the risk of heart disease. If you would like to report to the FDA a side effect youve had with Zetia, you can do so through MedWatch. POTS is a form of orthostatic intolerance that is associated with the presence of excessive tachycardia and many other symptoms upon standing. Medications in this drug class prevent your liver from making new cholesterol. For information on the effectiveness of Zetia, see the Zetia uses section below. After first three days stopped it for two days. Learn about the drugs dosages, forms, strengths, and more. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Side effects of Lipitor and Zetia that are similar include diarrhea and joint pain. The heartbeat increases with a feeling of the heart fluttering. Memory loss isnt a side effect of Zetia. Here are a few questions to get your discussion started with your doctor: To get information on different conditions and tips for improving your health, subscribe to any of Healthlines newsletters. Crestor contains the active drug rosuvastatin. This drug has not been studied in pregnant females.*. 6. However, if the side effects last longer than . Merck, the manufacturer of Zetia, offers a Patient Assistance Program. tender, swollen glands in neck. Zetia isnt a statin drug. Zetia can cause mild or serious side effects. It is created by eHealthMe based on reports of 45,364 people who have side effects when taking Zetia from the FDA, and is updated regularly. POTS affects the body's ability to pump blood from the legs to the rest of the body while standing. If you no longer need to take Zetia and have leftover medication, its important to dispose of it safely. The current stance of the Food and Drug Administration (FDA) is to avoid using expired medications. Zetia may cause serious side effects including: muscle pain, muscle tenderness or weakness, fever, unusual tiredness, and. Forget HDL and LDL. weakness and fatigue (tiredness) headaches. For this purpose, Zetia is used with a low-cholesterol diet and is taken with atorvastatin or simvastatin in adults and in children ages 10 years and older. Avoid storing this medication in areas where it could get damp or wet, such as bathrooms. POTS is an unusual condition in which your heart rate speeds up by 30 or more beats per minute with little or no change in blood pressure. Zetias mechanism of action is considered complementary to that of statins and fenofibrate. However, you may still experience muscle problems if you use Zetia alone. Diarrhea is a common side effect of Zetia. The generic is considered to be as safe and effective as the original drug. The cause of the disorder is unknown. Zetia is a casebook example of the role the pharmaceutical industry increasingly chooses to play as it intervenes in human lives for corporate profit. 2005-2023 Healthline Media a Red Ventures Company. Talk with your doctor if you have questions about using Zetia to lower your triglyceride levels. It may take about 2 weeks for your cholesterol levels to improve after you start taking Zetia. More common side effects in people taking Zetia* include: * In studies, these side effects were reported in people who took Zetia by itself. The manufacturer of Zetia hasnt stated whether the tablets can be crushed, split, or chewed. Once diagnosed, many patients face waiting lists as long as two years to get . They often originate at the base of the skull and spreading on the back of the head and neck. If youre concerned about joint pain while using Zetia, talk with your doctor. Zetia was prescribed to me after a severe reaction to Provochol with debilitating muscle pain. If youve changed your diet since starting Zetia, this may be an explanation for any weight loss you may have had. If your doctor confirms you had a serious allergic reaction to Zetia, they may have you switch to a different treatment. Other side effects not listed may also occur in some patients. But new medications can help lower cholesterol and improve heart health. Medications in the statin drug class work differently than cholesterol absorption inhibitors like Zetia. However, 0.5% of adults and children who took Zetia with a statin drug experienced muscle pain so bothersome that they had to stop treatment. And your doctor can use this information to adjust your treatment plan if needed. Zetia is approved to treat certain forms of high cholesterol in children ages 10 years and older when used with a low-cholesterol diet. This is because every persons body responds differently to medications. stomach pain. Muscle problems were reported in clinical studies of adults and children who took Zetia with statin drugs. If you have questions about the differences between Zetia and statin drugs, talk with your doctor. Hot and cold spells. Different interactions can cause different effects. Homozygous sitosterolemia is a genetic condition caused by a mutation (change) in the genes that control how plant sterols are cleared from your body. However, side effects are generally mild and go away as the body adjusts to the medication. Total cholesterol is the overall amount of cholesterol found in your blood. In Zetia's clinical studies, these were some of the side effects that occurred more often: pain in the arms or legs. The brand name for this drug combination is Vytorin. Zetia should be protected from moisture and shouldnt be stored in areas where it could get damp or wet, such as bathrooms. Fenofibrate is a drug used to lower your triglyceride levels. We've provided a list of the best at-home tests for. But the condition isn't well understood, and many patients are dismissed as having anxiety, delaying diagnosis. Examples of other drugs that may be used to treat primary high cholesterol include: Examples of other drugs that may be used to treat mixed high cholesterol include: Examples of other drugs that may be used to treat homozygous familial hypercholesterolemia include: Examples of other drugs that may be used to treat homozygous sitosterolemia include: You may wonder how Zetia compares with other medications that are prescribed for similar uses. They may have suggestions depending on your weight and health goals. And generics tend to cost less than brand-name drugs. Total cholesterol levels were reduced by an average of: LDL (bad) cholesterol levels were reduced by an average of: Homozygous familial hypercholesterolemia (HoFH) is a rare genetic condition caused by a mutation (change) in the genes that control how cholesterol is cleared from your body. Zetia is metabolized in the small intestine and liver. Porphyrias are rare, mainly genetic disorders that affect the body's ability to make hemoglobin. The dose of Zetia used for children is the same as the adult dose. Its not known if Zetia is safe to take during pregnancy. The following information is provided for clinicians and other healthcare professionals. Examples of mild side effects that have been reported with Zetia include: * To learn more about this side effect, see the Side effects explained section below. But, they can have side effects and might not be right for you. In these groups, joint pain occurred in: The length of time that adults and children experienced joint pain while taking Zetia in these clinical studies isnt known. However, your doctor will check your cholesterol levels about 4 weeks after you start treatment. Phase IV trials are used to detect adverse drug . If you have questions about weight changes while using Zetia, talk with your doctor. For those who aren't familiar with POTS, it is an often-disabling neurological condition that causes your heart rate to rise a great deal when you are upright, and often blood pressure drops when you are upright (when it should be rising), and it causes fainting, fatigue, headache, nausea, face and hand tingling, and blood pooling in legs. The only FDA-approved dosage of Zetia for children is 10 mg once a day. POTS is a form of "autonomic dysregulation" (a nervous system disorder) in which your heart rate spikes upon standing (among other symptoms). Or they may recommend a product you apply to your skin, such as hydrocortisone cream. This can cause Zetia to be less effective. Learn about side effects, dosage, uses, interactions, and more. The actual price youll pay depends on your insurance plan, your location, and the pharmacy you use. Memory loss isnt a side effect of Zetia. These lists contain up to 10 of the most common mild side effects that can occur with Zetia, with Lipitor, or with both drugs (when taken individually). Taking Zetia with cholestyramine can decrease the amount of Zetia in your body. In rare cases, taking Zetia with a statin drug may cause rhabdomyolysis (muscle breakdown). Zetia and Lipitor have some similar side effects and others that vary. Call 911 or your local emergency number if your symptoms feel life threatening or if you think youre having a medical emergency. This date is typically 1 year from the date they dispensed the medication. Zetia can cause certain side effects, some of which are more common than others. Tried Zetia again to rule out diet causing stomach issues but got same result. If you use Zetia and warfarin together, your doctor may want to monitor you more closely during your treatment. Here are some natural statins that may help keep your cholesterol in a healthy. POTS is commonly associated with low levels of fluid. Zetia (ezetimibe) is a prescription drug used to treat certain types of high cholesterol in adults and children. For some drugs, doing so may lead to unwanted side effects or overdose. High cholesterol can raise your risk of heart disease. Do my other medications increase my risk of side effects with Zetia? What causes POTS? Zetia is indicated as an adjunct to a low-cholesterol diet for treatment of the following types of hyperlipidemia: For treatment of primary hyperlipidemia, Zetia is indicated to reduce total cholesterol, low-density lipoprotein (LDL) cholesterol, non-high-density lipoprotein (non-HDL) cholesterol, and apiloprotein B (ApoB). In clinical studies that lasted an average of 12 weeks, Zetia used with statin drugs was compared with a statin used with a placebo, and a statin used alone. Get emergency medical help if you have signs of an allergic reaction to Zetia: hives; difficult breathing; swelling of your face, lips, tongue, or throat. The expiration date helps guarantee that the medication is effective during this time. So stopping Zetia may lead to an increase in your cholesterol levels. POTS was also linked, to a lesser degree, to Covid vaccination with an mRNA vaccine, according to the new study. Dr. John Szawaluk answered. 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